Mike Evans is dealing with a quad injury from training camp, but it doesn't sound serious. He missed a practice on August 3 (per ESPN), and an August 11 update says he's still nursing it — but Kyle Shanahan said the 49ers are just "being smart" with him and expect him back for the start of the season (from the Mike Evans page).
Some context that matters for fantasy: the 49ers WR room is banged up around him — Ricky Pearsall is out for the season (PCL), Christian Kirk has a calf strain, and rookie De'Zhaun Stribling has a hamstring issue. Flock Fantasy's training camp rundown flagged Evans' quad as part of that injury wave, but Evans' spot is secure.
The bigger concern is durability, not this specific tweak — he missed 8 games in 2025 with injuries, and as Josh & Hayden from Underdog noted, he "misses four games per season now because of his hamstrings" (). Keep an eye on his practice status, but as of now he's expected to be ready for Week 1.