Yep, Biadasz is essentially done for 2026. He tore his ACL and sustained additional damage to his left knee during a joint practice with the 49ers on August 18 (from the Tyler Biadasz page). ESPN confirmed it, and the Chargers have him listed as out indefinitely.
He signed a 3-year, $30M deal in the offseason to anchor the Chargers' interior line, so it's a brutal blow — especially for Justin Herbert and Mike McDaniel's offense, which relies heavily on center-QB synergy. Second-round rookie Jake Slaughter is expected to step in as the starter (from the Tyler Biadasz page).